Vicious circle of stress in HPU
Because some enzymes of the heme synthesis do not work properly in the HPUler, toxic hemopyrrollactam (HPL) is produced instead of functional heme. In order to make this substance water-soluble and to get rid of it in the urine, the body attaches zinc, vitamin B6 and partly also manganese to HPL. This means that large quantities of these important micronutrients are constantly lost to the HPU user.
Under stress (whether homemade or from outside) the body produces more haemopyrrolactam – and thus loses more zinc, vitamin B6 and manganese.
This in turn weakens the HPUler, which increases its susceptibility to stress. A vicious circle has begun.
The synthesis (production) of haem takes place in the intermembrane space of the mitochondria. These cell organelles are also known as “power plants of the cell”, although they perform far more functions than producing energy for the body in the form of ATP. In addition to iron, vitamin B2 and glycine, the body also needs vitamin B6 and zinc to form heme. The latter are often deficient in HPU.
Oxygen radicals (Reactive Oxygen Species = ROS) are naturally formed in the mitochondria. Although the mitochondria form these reactive oxygen molecules, they react very sensitively to them. Therefore, there are various protective systems in the body that render ROS harmless. Enzymes are part of the ROS protection system:
- Superoxide dismutase (SOD 1, 2 and 3) -> SOD2 only works when manganese is available, SOD1 and SOD3 each require zinc and copper)
- Catalase (requires iron)
- Gluthation peroxidase (requires selenium)
A lack of the micronutrients needed for mitochondrial damage and energy deficiency. A lack of energy in turn increases the feeling of stress. Thus the stress spiral of the HPUler leads further and further downhill.
Relaxation methods are not a luxury for the HPUler, but essential tools to be able to better manage the available energy.
Relaxation can be achieved individually in different ways. Find out what is good for you and push your energy level up again. This can be done, for example by:
- regular yoga
- a walk in the fresh air