HPU- Therapy

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HPU - What can I do?

What happens next?

You have learned through a urine test that you are affected by the metabolic disorder HPU (Hemopyrrollactamuria). At first, this can feel overwhelming, as HPU is a fairly complex condition with several important aspects to consider.

My advice: Take enough time to learn about HPU so that you can better understand how to support your body in the best possible way.

Many people with HPU start taking an HPU combination supplement too quickly. However, this can lead to unwanted side effects that can easily be avoided.

“Important: There is no quick fix! A complete regression of HPU symptoms usually takes months and depends on age and the measures taken.”

How to achieve your goal

Although HPU can manifest itself through a wide variety of symptoms, all people affected by HPU benefit from the following fundamental measures:

a diet adapted to HPU, effective stress management, regular physical activity without overexertion, a micronutrient supply tailored to individual needs, and a low-toxin lifestyle.

Not taken seriously by conventional medicine

Many HPU sufferers go through a medical odyssey before their diagnosis, with unsatisfactory therapeutic success. In support groups, they report feeling ‘not taken seriously,’ having their symptoms dismissed as psychological (‘we can’t find anything physically wrong, your problems must be psychological’), or receiving pure symptom management (painkillers for chronic headaches or abdominal pain)

Since HPU can also be accompanied by psychological disorders such as anxiety and panic attacks, depression, ADHD, as well as high sensitivity, many HPU sufferers end up in psychotherapeutic practices.

Many doctors either reject HPU on principle or are not well-acquainted with the special needs of HPU sufferers. Therefore, it is essential that those affected closely educate themselves on the subject.

In my book, I explain exactly how you can help yourself.

About the book

Compensation of micronutrients

The reason for the metabolic disorder HPU is not yet fully understood. Today, we assume that the synthesis of the heme molecule is disrupted in HPU sufferers. As a result, the body produces an incorrectly folded heme, which cannot function properly due to its flawed structure. Since the incorrectly folded heme is toxic to the body, it must be eliminated. This is achieved by excreting the heme building blocks (pyrroles) through the kidneys (these pyrroles are measured with the HPU test).

Although this solves the problem of toxic heme for the time being, the body loses important micronutrients due to high oxidative stress, which are urgently needed elsewhere. A fundamental pillar of HPU therapy is therefore the adequate supply of the body with micronutrients. These primarily include minerals such as

Zinc

Activated vitamin B6 (P5P)

Manganese

Through the intake of these 3 micronutrients, heme synthesis also normalizes. The body produces more “healthy” heme and less misfolded heme, which it needs to eliminate. The amino acid glycine, which is essential for heme production, can also provide supportive effects for heme synthesis. However, most people with HPU are still deficient in numerous other micronutrients, as laboratory tests show.

IMPORTANT: A successful HPU therapy typically requires far more than just taking a few micronutrients. The nervous system, nutrition, stress, detoxification, and hormones all play a significant role and must also be considered in therapy.

How long does the therapy take?

Micronutrients need to be supplied for life in most people with HPU – more during stressful phases of life and less during calmer periods. An improvement of symptoms can be expected in adults 4 to 6 months after starting therapy, while in children it may occur significantly earlier.

In many people with HPU, psychological symptoms improve within the first 3–4 months after starting treatment, and physical symptoms typically begin to improve from around the 4th month. However, the timing of improvement varies greatly from person to person depending on the type and severity of symptoms.

Managing HPU yourself?

The HPU condition is likely to persist for a lifetime, but it can be very effectively balanced through proper micronutrient therapy and an adapted lifestyle. It is important that you understand what is different in your metabolism and what you can do yourself to help your body feel better again.

If you want to take your health into your own hands, join my HPU starter program and learn step by step how to bring your HPU metabolism back into balance. This knowledge will stay with you for the rest of your life.

From the blog

Keto for HPU: How a Ketogenic Diet Can Help

Keto for HPU: How a Ketogenic Diet Can Help

A ketogenic diet is a very low-carbohydrate way of eating in which the body primarily uses ketone bodies instead of glucose for energy production. Is this beneficial for someone with HPU?

Disclaimer and general note on medical topics:

The contents presented here are intended exclusively for neutral information and general further education. The texts do not claim to be complete, nor can the topicality, correctness, and balance of the information presented be guaranteed. The texts in no way replace professional advice from a doctor or pharmacist and they must not be used as a basis for independent diagnosis and the start, modification, or termination of a treatment for diseases. Always consult your trusted doctor for health questions or complaints! I assume no liability for inconveniences or damages resulting from the application of the information presented here.